WebNov 4, 2024 · PTPMT1 and cardiolipin levels were significantly reduced in Sugen/hypoxia mice, while miR-150 supplementation restored their expression to the level seen in healthy mice (Figures 6A–6C). Overexpression of PTPMT1 and miR-150 significantly elevated cardiolipin levels in cultured endothelial cells (p < 0.01 and p < 0.05, respectively) ( Figure … WebCM-H 2 DCFDA staining showed that ROS accumulated more dramatically in PTPMT1 KO cells under hypoxia than in normoxia ( Figures 2E and S1H). MitoPY1 is a small-molecule fluorescent probe that ...
Ptpmt1 induced by HIF-2α regulates the proliferation and …
WebNov 4, 2024 · PTPMT1 and cardiolipin levels were significantly reduced in Sugen/hypoxia mice, while miR-150 supplementation restored their expression to the level seen in healthy … WebNov 1, 2024 · PTPMT1 and car diolipin levels w ere significantly reduced in Suge n/hypoxia mice, while 196 miR-150 supplementation restored their expression to the level seen in healthy mice ( Figure princetop corporate training
Ptpmt1 induced by HIF-2α regulates the proliferation and glucose ...
WebOct 1, 2015 · In this study, we presented evidence that mitochondrial phosphatase Ptpmt1 is a hypoxia response molecule that regulates cell proliferation, survival and glucose … WebFeb 10, 2015 · Lysates from ptpmt1 +/ ... SDH activity, supercomplex distribution in the mitochondria, and metabolic adaptation of mitochondria to starvation or hypoxia/reoxygenation (Acín-Pérez et al., 2014). Therefore, in addition to increasing glucose uptake by stimulating insulin secretion, PTPMT1 inhibition may increase the rate of … WebMar 15, 2024 · Download Citation PTPMT1 regulates mitochondrial death through the SLC25A6-NDUFS2 axis in pancreatic cancer cells Pancreatic ductal adenocarcinoma is a highly malignant cancer with poor ... prince topher full name